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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYFIP1
All Species:
19.39
Human Site:
Y366
Identified Species:
32.82
UniProt:
Q7L576
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L576
NP_001028200.1
1253
145182
Y366
F
I
S
E
L
A
R
Y
S
N
S
E
V
V
T
Chimpanzee
Pan troglodytes
XP_001137120
1278
148380
R365
R
F
I
S
E
L
A
R
Y
S
N
S
E
V
V
Rhesus Macaque
Macaca mulatta
XP_001105005
1359
156392
R446
R
F
I
S
E
L
A
R
Y
S
N
S
E
V
V
Dog
Lupus familis
XP_536156
1212
140594
Y366
F
I
S
E
L
A
R
Y
S
N
S
E
V
V
T
Cat
Felis silvestris
Mouse
Mus musculus
Q7TMB8
1253
145223
Y366
F
I
S
E
L
A
R
Y
S
N
S
E
V
V
T
Rat
Rattus norvegicus
NP_001100987
1253
145239
Y366
F
I
S
E
L
A
R
Y
S
N
S
E
V
V
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508077
1255
145699
R365
R
F
I
S
E
L
A
R
Y
S
N
S
E
V
V
Chicken
Gallus gallus
XP_414567
1253
145683
R365
R
F
I
S
E
L
A
R
Y
S
N
S
E
V
V
Frog
Xenopus laevis
Q6GQD1
1253
145619
R365
R
F
I
S
E
L
A
R
Y
S
N
S
E
V
V
Zebra Danio
Brachydanio rerio
Q90YM8
1253
145156
Y366
F
I
S
E
L
A
R
Y
S
N
S
E
V
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VF87
1291
149242
E361
D
H
V
K
Y
I
S
E
L
A
R
Y
T
N
E
Honey Bee
Apis mellifera
XP_395632
1292
149877
E363
D
H
V
K
Y
I
S
E
L
A
R
Y
S
N
E
Nematode Worm
Caenorhab. elegans
O44518
1262
144995
T360
S
D
H
E
S
Y
V
T
Q
F
A
K
I
N
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q5S2C3
1283
145467
M375
T
I
R
F
A
S
S
M
N
Q
L
L
L
L
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.9
81
96
N.A.
99
99.1
N.A.
87.4
87.7
86.9
92.5
N.A.
65.4
67.8
51.7
N.A.
Protein Similarity:
100
92.1
86.9
96.4
N.A.
99.6
99.7
N.A.
93.7
94
93.8
96.9
N.A.
80.4
81.2
70.8
N.A.
P-Site Identity:
100
6.6
6.6
100
N.A.
100
100
N.A.
6.6
6.6
6.6
100
N.A.
0
0
6.6
N.A.
P-Site Similarity:
100
20
20
100
N.A.
100
100
N.A.
20
20
20
100
N.A.
6.6
6.6
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
36
36
0
0
15
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
43
36
0
0
15
0
0
0
36
36
0
15
% E
% Phe:
36
36
0
8
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
15
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
43
36
0
0
15
0
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
15
0
0
0
0
0
0
0
8
0
0
8
% K
% Leu:
0
0
0
0
36
36
0
0
15
0
8
8
8
8
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
36
36
0
0
22
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% Q
% Arg:
36
0
8
0
0
0
36
36
0
0
15
0
0
0
0
% R
% Ser:
8
0
36
36
8
8
22
0
36
36
36
36
8
0
0
% S
% Thr:
8
0
0
0
0
0
0
8
0
0
0
0
8
0
36
% T
% Val:
0
0
15
0
0
0
8
0
0
0
0
0
36
72
36
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
15
8
0
36
36
0
0
15
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _